GENESIS: Drug Racket.htm
Pharmaceutical Drug Racket
PART ONE
The industry depends on your ill health for its profit
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The Rocketing Cost of Health Care. Medical "ignorance" is costing us billions', reads a heading in The Daily Telegraph Mirror of 24th February 1991 over an article as follows:
Writing in an article in The Sunday Telegraph on October 27 1991, the Federal Minister for Community Services and Health, Brian Howe, expresses his concern:
The rocketing cost of health care in Australia is not unique to this country, but is typical of all industrial nations. In his book "Limits To Medicine"(1979), prominent medical historian, Ivan Illich writes:
Are We Consuming Too Many Drugs? As was reported in The Bulletin, 24 March 1992, one of the fastest-growing components of Australia's costly health bill is the pharmaceutical drug trade, which accounts for $2 billion a year for prescription drugs. The Bulletin article reveals that "Australians are on a drug binge, consuming twice as many antibiotics per capita as Sweden and far more than the US and Britain". The situation in the United States and Britain sixteen years ago was bad enough for Illich to write:
At the time of Illich writing this (1976), it is estimated that 50 to 80% of adults in the United States and the United Kingdom were consuming a medically prescribed chemical every 24 to 36 hours. In his book Confessions of a Medical Heretic (1980), famed medical writer and paediatrician, Dr. Robert Mendelsohn, accused doctors of having "seeded the entire population with these powerful drugs". Mendelsohn further states that "Every year, from 8 to 10 million Americans go to the doctor when they have a cold. About ninety-five per cent of them come away with a prescription - half of which are for antibiotics." A recent report by the National Health Strategy (1992) has pointed out that 160 million prescriptions are being dispensed from Australian pharmacies every year, and an estimated further 20 million from hospital pharmacies. This figure represents a 640% increase since 1949, during which time 280,719 prescriptions were dispensed. As reported in Clinical Pharmacology and Therapeutics (1976), a study in a large country town in Australia has revealed that people who reported no illness took as many drugs as those who reported a chronic and acute illness. The authors noted that "the rate of increase in drug usage at around 25% per year can only be explained by increased drug usage of both prescription and OTC (over-the-counter) drugs by the majority of the population." At the time of the report Australians were consuming half the number of prescription drugs compared to today. Recent figures of how many OTC or non-prescription drugs consumed by Australians are difficult to obtain. Industry sources are reluctant to divulge this information. However, a study by the Health Commission of NSW in 1979 that stated that "at present Australia has one of the leading rates of per capita consumption of analgesics in the world", quoted 1973 figures for sales of OTC medications at $166 million. It is estimated that in 1991 $1.4 billion was spent on OTC medications which, when added to the $2 billion spent on prescription drugs, totals a staggering $3.4 billion. Drugs In The Food We Eat Apart from the vast number of drugs taken directly, people are also unknowingly consuming large amounts of drugs and other chemical substances indirectly from the food they eat. Most food industries rely on chemical substances from soil to supermarket and animal products industries are by far the most excessive users of these substances. The avalanche of drug and chemical usage by these industries occurred with the shift in production methods from free-range farming to factory and feedlot farming in the last 20 to 30 years. Over 15 years ago, there were more than 1,000 drug products and as many chemicals i use by the livestock and poultry producers in the United States. Also, more than 40% of the antibiotics and other antibacterials produced every year in the US were used as animal feed additives and for other animal purposes. Almost 100% of poultry, 90% of pigs and veal calves, and 60% of cattle have regular amounts of antibacterials added to their feed. Seventy-five per cent of hogs have their feed supplemented with sulphur drugs and almost 70% of US beef is from cattle fed on hormones to promote growth. The amount of drugs and chemical substances used on farm animals in the industrialised nations is enormous. The Consequences As could be expected, one result of the vast over-consumption of drugs is the astronomical profits generated by the drug industry. Since the beginning of the sixties, drug industry profits (as a percentage of sales and company net worth) have surpassed all other manufacturing industries listed on the Stock Exchange. Another result is the inevitable deterioration of public health. According to the Food and Drug Administration (FDA), 1.5 million Americans were hospitalised in 1978 as a consequence of taking drugs and some 30% of all hospitalised people are further damaged by their treatments. Every year, an estimated 140,000 Americans are killed because of drug-taking and one in seven hospital beds is taken up by patients suffering from adverse drug reactions. A report by the General Accounting Office in the United States revealed that 51.5% of all drugs introduced between 1976 and 1985 had to be re-labelled because of serious adverse reactions found after the marketing of these drugs. These included heart, liver and kidney failure, foetal toxicity and birth defects, severe blood disorders, respiratory arrest, seizures and blindness. The changes to the labelling either restricted a drug's use or added major warnings. How Common Are Drug Adverse Reactions? According to the Adverse Drug Reaction Advisory Committee (ADRAC), the official federal government body responsible for monitoring the safety of drugs already in use: "There is a dearth (scarcity) of published information on the medical and economic importance of adverse drug reactions in Australia." However, a recent study (1991), cited by the National Health Strategy report on drug use, claims that in 1987-88 there were between 30,000 and 40,000 hospital admissions in Australia because of drug-taking and also that adverse drug reactions (ADRs) would have been a major factor for between 700 to 900 deaths a year. There are some who are highly critical of the official estimation of the extent of drug reactions within communities. Dr. Julian Gold, head of the National Health Surveillance Unit of the Commonwealth Institute of Health, whose job as a medical epidemiologist is to collate information on the total health environment, estimates that up to 40% of all patients in Australia may actually be victims of doctor-induced (iatrogenic) illnesses. A 40% figure has also been estimated for the United Kingdom. Generally, of this amount half are from drug reactions. Under-Reporting of Drug Reactions Many drug reactions go unnoticed. In Controversies in Therapeutics (1980), Dr. Leighton Cluff comments:
According to a US Senate Select Committee, hundreds of victims of the drug chloramphenicol died undiagnosed in the United States. Dr. Leighton Cluff further states: "Physicians are currently not required to report observed cases of drug-induced diseases to a centralised registry." In Australia, the reporting by doctors of adverse reactions is voluntary. Postage-paid forms are provided to doctors who are asked to report adverse reactions to ADRAC. Due to complacency, ignorance, and perhaps guilt that their prescribed treatment has caused harm, most doctors fail to fill in these forms. Even when doctors are willing to report ADRs, there are significant problems that add to the under-reporting of drug reactions. ADRs can sometimes be difficult to identify and Dr. Judith Jones, Director of the Division of Drug Experience at the FDA in the United States, has listed three factors that inhibit detection: 1. Difficulty in distinguishing the reaction from the underlying diseases, or negative placebo effects. 2. Many ADRs have a silent nature and if not specifically looked for they may not be found. For example, kidney and liver damage. 3. In multi-drug regimes it is difficult to identify the particular drug which is causing the suspected reaction. Only 5 to 10% of actual cases are believed to be reported to ADRAC. In the United Kingdom, which has a similar reporting system to ours, only 1 to 10% of cases are revealed. The inadequacy of the reporting system in the UK was demonstrated by the fact that only about a dozen of the 3,500 deaths, later linked with isoprenaline aerosol inhalers during the 1960's were actually reported by doctors at the time. Because most adverse reactions to drugs go unreported, the official estimates must be only the tip of the iceberg. Who Is To Blame For Drug Damages? Not only do health officials grossly underestimate the extent of drug reactions, they also try to convince the unwary public that drug-related illnesses are largely due to inappropriate drug usage. Officials try to place the onus on consumers and prescribing doctors, and reassure the public that problems rarely occur if drugs are used as prescribed. To protect the drug industry from blame, officials purposely ignore the fact that most drugs are harmful; even if used "appropriately". Epidemic Iatrogenesis On doctor or hospital induced illnesses, a once active member of the Doctors' Reform Society and author of the book Medicine Out of Control (1979), Dr. Richard Taylor, writes:
Dr. Beaty and Dr. Petersdorf write in the Annals of Internal Medicine (1966):
Taylor, Beaty and Petersdorf are not alone in the ir criticisms of allopathic medicine, Also known as "modern medicine." More and more physicians and other medical professionals are becoming increasingly disillusioned with their own profession. Allopathic medicine has become more of a band-aid treatment. In their attempts to "patch-up" symptoms of illnesses, doctors are known to use poisonous chemical-based drugs, radical surgical operations and dangerous radiation, which often cause more harm than the original problem. Apart from introducing more illnesses, allopathic "treatments" mask symptoms of the underlying causes of the illness, which inevitably makes it more difficult to detect and treat, and thereby causing it to become more chronic. Allopathic medicine can be useful and sometimes life-saving for emergency situations (for example, car accidents), yet its harmfulness and ineffectiveness cannot be over-stated. A prominent critic of allopathic medicine has been the late Dr. Robert Mendelsohn, who exposed much corruption in American medicine. Dr. Mendelsohn published the following best-selling books: Confessions of a Medical Heretic (1980), Mal(e) Practice: How Doctors Manipulate Women (1982), and How to Raise a Healthy Child In Spite of Your Doctor (1987). These books are highly recommended. In Limits to Medicine, Ivan Illich warns:
Doctors Strike: Death Rate Drops With the above in mind, it is not surprising that during a one month physicians' strike in Israel in 1973, the national death rate reached the lowest ever. According to statistics by the Jerusalem Burial Society, the number of funerals dropped by almost half. Identical circumstances occurred in 1976 in Bogata, the capital city of Columbia where, there, the doctors went on strike for 52 days and, as pointed out by the National Catholic Reporter, during that time the death rate fell by 35%. This was confirmed by the National Morticians' Association of Columbia. Again in California a few years later, and in the United Kingdom in 1978, identical events have occurred. The Small Role Of Medicine In Mortality It is important to understand that the vast majority of people are born healthy and, if not tampered with, are "equipped" to remain healthy throughout life. We seldom require intervention with illnesses because the body, as well as the mind, is usually able to defend and heal itself against disease and injury. Only infrequently do we require assistance. Medical intervention is the least important of the four factors that determine the state of health. The Center For Disease Control analysed data on the ten leading causes of death in the United States, and determined that lifestyle was by far the most important factor (51%) followed by environment (20%), biologic inheritance (19%) and lastly medical intervention (10%). According to a classic analysis by Professor Thomas McKeown of Birmingham University, medicine played a very small role in extending the average lifespan in Britain over the past few centuries, the major benefit to people having been improvements in nutrition and public sanitation. Researchers, John McKinlay and Sonja McKinlay came to similar conclusions. They showed that medical intervention only accounted for between 1 and 3.5% of the increase in the average lifespan in the United States since 1900. The above statistics prove that health depends primarily on prevention, through hygiene and proper nutrition. In the few instances, when therapy of any sort is warranted, it must deal with the whole person (the Holistic approach), treating the actual cause rather than attempting to isolate and suppress symptoms. Allopathic medicine fails in comparison to the holistic approach, and in many instances damages the patient even more the illness it intends to treat. Natural medicines and therapies, such as herbalism, homeopathy, naturopathy, osteopathy and acupuncture, to name a few, work on the holistic approach, and are generally far superior in safety and efficacy than allopathic "treatments". Drug Companies Bribing Doctors A major reason why health care is in such a shambles is that the medical establishment has allowed itself to be bought off by the pharmaceutical industry, whose prime motive is profit. In the book Dissent in Medicine - Nine Doctors Speak Out (1985), Dr. Alan Levin writes:
A double page article titles "$200m `bribe' to lure our doctors" appearing in The Sun Herald (18 August, 1992), reported that:
The article cited Theo van Lieshout, secretary of the NSW Doctors' Reform Society, as saying that 50% of drugs on the market did not exist 10 years ago - and doctors had not learned about them in medical school. busy physicians therefore rely mainly on drug company sales staff to tell them about new medications. As reported in The Bulletin (24 March 1991), Dr Ken Harvey stated: "The students concede concern. The problem is, after five years out in practice, with six drug reps a week coming in, they have gone away from prescribing sensibly and by scientific name to prescribing the brand promoted by the last rep who walked in." University Scientists - The Willing Pawns
Dr Alan Lewis is an adjunct Associate Professor of Immunology and Dermatology at the University of California. He is a Fellow of the American College of Emergency Physicians, the College of American Pathologists, and the American Society of Clinical Pathologists. Dr Lewis is also a recipient of fellowships and awards from Harvard Medical School and other medical institutions, and was director of various research laboratories. Ivan Illich echoes Lewis' last comment: "The medical establishment has become a major threat to health. The disabling impact of professional control over medicine has reached the proportions of an epidemic." The Drug Story How the pharmaceutical industry took control of the hospitals, universities, research and other institutions in the early part of this century is amply demonstrated by world-famous medical historian and author, Hans Ruesch, in his devastating expose: Naked Empress or The Great Medical Fraud (1992). The book is an absolute must to read. Naked Empress exposes massive corruption and fraud in medicine, science, industries, governments, media and various organisations. The importance of this book cannot be over-stated. In Naked Empress, Ruesch cited another important expose titled The Drug Story (1949) by American investigative reporter, Morris A. Bealle. According to Bealle: "America's largest and most ruthless industrial combine, the Rockefeller Empire" (which was built on Standard Oil Company) in the early part of this century became interested in the drug trade after making breath-taking profits from palming off bottled petroleum called Nujol as a supposed cure for cancer and later constipation. In 1939 the Drug Trust was formed by an alliance of the world's two greatest cartels in world history - the Rockefeller Empire and the German chemical company I.G. Farben industrie (I.G.Farben). Drug profits from that time onwards curved upwards into gigantic proportions and by 1948 it became a 10-billion-dollar-a-year industry. I.G. Farben's unsavoury past is highlighted by the fact that during the Second World War it built and operated a massive chemical plant at Auschwitz using slave labour. Approximately 300,000 concentration-camp workers passed through I.G. Farben's facilities at Auschwitz and at least 25,000 of them were worked to death. Also, others were brutally killed in I.G. Farben's drug testing programs. Twelve of I.G. Farben's top executives were sentenced to terms of imprisonment for slavery and mistreatment offences at the Nuremberg war crime trials. Hoechst and Bayer, the largest and third largest companies in world pharmaceutical sales respectively, are descended from I.G. Farben. In September 1955, Hoechst appointed Friedrich Jaehne, a convicted war criminal from the Nuremberg trials, as chairman of its supervisory board. Also, a year later, Bayer appointed Fitz ter Meer, another convicted war criminal, as chairman of its board. On the Rockefellers' moves towards "influencing" medical colleges and public agencies in the United States, Bealle writes:
The Rockefellers did not restrict their "educational" activities to the US alone. In 1927 they formed the International Education Board which "donated" millions of dollars to foreign universities and politicos, with all the usual strings attached. As these huge amounts of money were being "donated" to drug-propagandising colleges, the Rockefeller interests were expanding world-wide. It was large enough 40 years ago for Bealle to state:
The keystone of this mammoth industrial empire is the Chase National Bank with 27 branches in New York City and 21 in foreign countries (now renamed the Chase Manhattan Bank with over 200 branches in the US and abroad). Not the least of its holdings are in the drug business. The Rockefellers own the largest drug manufacturing combine in the world, and use all of their other interests to bring pressure to increase the sale of drugs." The Not-So-Independent Media Instrumental in Rockefellers' moves towards making the world drug-dependent is their enormous influence on the media. Commenting on this, Ruesch explains:
Ruesch showed how the above-mentioned international media were taken over by the Drug Trust and he further explains:
Thus newspapers continue to be fed constantly with propaganda about drugs and their alleged value, although 1.5 million people landed in hospitals in 1978 because of medication side-effects in the US alone, and despite recurrent statements by intelligent and courageous medical men that most pharmaceutical items on sale are useless and/or harmful. Among the many publications owned by the Rockefeller Drug Trust, are: Fortune, Life, Time, Readers Digest and Newsweek magazines, and the Encyclopedia Britannica. These publications are constantly pushing drugs. Food and Drug Administration - serving who? Leaving no stone unturned, Ruesch shows how the Drug Trust, in securing their drug interests, planted stooges into senior positions of colleges, universities, and government bodies. About the Food and Drug Administration, Ruesch charges:
Ruesch cited Morris Bealle who wrote that the FDA "is used primarily for the perversion of justice by cracking down on all who endanger the profits of the Drug Trust." Ruesch further states:
The Undeclared War on Natural Medicine The Civil Abolitionist carried an article rightly titled "FDA: The American Gestapo Prosecutor or Persecutor?", which reported that on May 6, 1992, the clinic of Jonathan Wright MD, a highly regarded nutrition specialist, was assailed by 22 armed men because the doctor had been treating his patients with safe natural substances that didn't meet the FDA's approval. During the SWAT type attack the front door was kicked open, guns were pointed directly at staff and the shocked patients were herded into a room. Also, patient records, equipment, business records and vitamin supplies were confiscated. At the time of the article, the FDA has not yet filed charges against Dr Wright. During the last year, similar actions have taken place against three manufacturers of vitamin supplements [Allergy Research, Thorne Research and Highland Laboratories]. In Australia, a repeal of Schedule 1, Exemptions of the Therapeutic Goods Act, scheduled for January 1994, would minimise access to natural therapy remedies by natural therapists and would threaten the existence of the natural therapy profession and manufacturers of natural therapy remedies. Corrupt FDA Officials In their August-September 1992 issue, NEXUS Magazine reported that it is a matter of public record that the FDA indulges in the following practices: * Many of the so-called `research grants' that the FDA receives are `donated' by the very drug companies they were supposed to be regulating. * Mid- and upper-level FDA officials enjoy `revolving door' status when they leave the FDA, wherein they go to cushy, well-paying jobs in those very same drug companies they were supposed to have been regulating. * Currently, 150 top FDA officials hold significant amounts of stock in the pharmaceutical companies they were supposed to be regulating. American `Murder' Association The AMA, once openly declared by Dr. Richard Kunnes at an AMA convention that it shouldn't be the acronym for American Medical Association but for American `Murder' Association, is, according to Morris Bealle, the front for the Drug Trust. When the FDA has to put an independent operator out of business, they get the AMA to furnish quack doctors to testify that while often knowing nothing about the product involved, it is their considered opinion that it has no therapeutic value. Bealle cited an example in which the AMA furnished ten medicos to testify in court that "vitamins are not necessary to the human body", in order to close down an independent distributor of natural vitamins. J.W. Hodge, MD, of Niagra Falls, New York, writes about the AMA:
It comes as no surprise that the Australian counterpart, the Australian Medical Association, in conjunction with the Royal College of General Practitioners, as reported in The Australian (July 21, 1992) are pushing for legislation that would cause medical doctors using natural therapies to lose Medicare status. This would mean that their patients would not be able to have bills rebated by Medicare. The Masters of Government If to you it seems inconceivable that governments have allowed a ruthless industry to dictate health matters, consider what Woodrow Wilson stated during his first presidential campaign in 1912:
Writes Ruesch:
Morris H. Rubin, editor and publisher of The Progressive, writes in an article in January 1977:
"The oil lobby, perhaps the most powerful lobby on Earth, is almost matched by hospital owners and doctors." President Carter, 1979. Incidentally, in 1980, Exxon became America's largest corporation. Exxon is the new name of the old Rockefeller Standard Oil Trust. For a further insight on how the cartels have turned democracies into private oligarchies, the books Naked Empress by Hans Ruesch, and None Dare Call It Conspiracy (1971) by investigative journalist Gary Allen, are highly recommended. Australia's Health System Under Threat From US Corporations Because the Australian Government can no longer afford to fund our ailing public health care system, privatisation is inevitable. A major concern is that the ruthless US corporations will be the principal buyers. An article appearing in The Daily Telegraph Mirror (1 October 1992) titles "US Giants Threat To Hospitals", reports:
PART TWO Corporate Crime In The Pharmaceutical Industry. The sordid behaviour of today's pharmaceutical corporations has been further demonstrated by Dr. John Braithwaite, now a Trade Practices Commissioner, in his devastating expose, Corporate crime in the Pharmaceutical Industry(1984).
Describing many examples of corporate crime, which shows the depth and seriousness of the crime problem in the pharmaceutical industry, Dr. Braithwaite's revealing study is based on extensive international research, including interviews of 131 senior executives of pharmaceutical companies in the united States, the United Kingdom, Australia, Mexico, and Guatemala. The book shows how pharmaceutical multinationals defy the intent of laws regulating safety of drugs by bribery, false advertising, fraud in the safety testing of drugs, unsafe manufacturing processes, smuggling and international law evasion strategies. At the time of researching the subject, Braithwaite was a research criminologist at the Australian Institute of Criminology and a Fulbright Fellow affiliated to the University of California, Irvine, and the United Nations Center on Transnational Corporations. Fraud in Drug Testing "Data fabrication is so widespread," says Dr. Braithwaite, "that it is called 'making' in the Japanese pharmaceutical industry, 'graphiting ' or 'dry labelling' in the United States." He further states:
In his book Braithwaite cited former FDA Commissioner Goddard expressing his concerns over research dishonesty at a Pharmaceutical Manufacturers Association Meeting in 1966:
Goddard's immediate successor at the FDA, Dr. Ley, spoke before the US Senate hearings of a spot check that showed up the case of an assistant professor of medicine who had reputedly tested 24 drugs for 9 different companies. "Patients who died while on clinical trials were not reported to the sponsor," an audit revealed. "Dead people were listed as subjects of testing. People reported as subjects of testing were not in the hospital at the time of tests. Patient consent forms bore dates indicating they were signed by the subjects after the subjects died." Another audit looked at commercial drug-testing firm that had apparently worked on 82 drugs and 28 sponsors:
Between 1977 and 1980 the FDA have discovered 62 doctors who had submitted manipulated or downright falsified clinical data. A study conducted by the FDA has revealed that one in five doctors investigated, who carry out field research of new drugs, had invented the data they sent to the drug companies, and pocketed the fees. Citing case examples, Dr. Braithwaite states:
According to dr. Judith Jones, Director of the Division of Drug Experience at the FDA, if the data obtained by a clinician proves unsatisfactory towards the drug being investigated, it is quite in order for the company to continue trials elsewhere until satisfactory results and testimonials are achieved. Unfavourable results are very rarely published and clinicians are pressured into keeping quiet about such data. It is very easy for the drug company to arrange appropriate clinical trials by approaching a sympathetic clinician to produce the desired results that would assist the intended application of the drug. The incentive for clinical investigators to fabricate data is enormous. As much as $1,000 per subject is paid by American companies, which enables some doctors to earn up to $1 million a year from drug research, and investigating clinicians know all too well that if they don’t produce the desired data, the loss of future work is inevitable. University Scientists - the More Than Willing Pawns Braithwaite cited an FDA survey of safety testing violations that have shown that university laboratories had the worst record for violations than all other laboratories in the survey. Braithwaite writes:
Inappropriate Clinical Trials Even if data obtained from clinical trials is not falsified, it is of little worth, because they are not performed appropriately. Trials involve relatively small numbers of people; so many harmful effects of a new drug appear only when it has been marketed and widely used. Furthermore, the subjects taking part in the trial usually do not represent those who will use the drug after its approval. Very young or elderly people, women of child-bearing age and people with liver or kidney disease are usually not included in clinical trials, although such people may be given the drug after it is marketed. Also, optimal dosages for adults are calculated on the basis of what is most effective for an average-size adult. Many adults differ from this average, and about 45% of ordinary adults are probably going to respond atypically to some classes of drugs. Drug Companies Concealing and Misrepresenting Dangerous Drug Effects Dr. Braithwaite cited a number of cases where drug companies concealed and misrepresented dangerous effects of drugs noted by their own investigators. Braithwaite writes:
In Whose Interests Are Drugs Tested? The testing procedures of drugs are primarily performed to ensure the approval and marketing of these substances: despite the fact they are usually unsafe and ineffective. If drug companies were truly ethical and responsible, the vast majority of drugs would not have been allowed on the market in the first place. West Germany's prestigious weekly, Der Spiegel (24 June 1985), carried a most revealing article titled, "how the Pharmaceutical industry Bought Bonn". The article, which featured on the front page and covered several pages, contributes to the real motives behind drug testing. in essence, the article could just as well apply to the United States, Britain and most other industrial nations. the following is a brief excerpt:
Many of the politicians and public officials who contribute to the acceptance of these guidelines were named in the article, and the bribes they pocketed were itemised. Fraudulent Animal Testing The most blatantly fraudulent procedure of drug testing is the testing of these substances using animal models - a practice often termed 'vivisection'. To begin with, many of the most common or life-threatening side-effects cannot be predicted by animal tests. For instance, animals cannot let the experimenter know if they are suffering from headache, amnesia, nausea, depression and other psychological disturbances. Allergic reactions, some blood disorders, skin lesions and many central nervous system effects are even more serious examples that cannot be demonstrated by animal models. According to one of the world's best known toxicologist's, Professor Gerhardt Zbinden, from Zurich's Institute of Toxicology, "Most adverse reactions that occur in man cannot be demonstrated, anticipated or avoided by the routine subacute and chronic toxicity experiment." Professor Zbinden has shown that of the 45 most common adverse reactions only three may possibly be predicted, and of the remaining 42, "only in exceptional cases can they be predicted from routine toxicologic tests." Species Differences Apart from the effects that cannot be demonstrated in animals, another very fundamental problem exists with testing substances using animals. Each individual species of animal has a unique genetic make-up. Any genetic differences predetermine massive variations in histology (structure, composition and function of tissues), biochemistry (chemistry of living organisms), morphology (structure of organisms), physiology (function of living organisms), and other species characteristics. because each animal species is different, substances that are tested on them for 'safety' and 'effectiveness' will have a different effect on each individual species. This has been amply demonstrated by Professor Piere Croce, former animal experimenter, and world-renowned author and medical researcher, in his revealing treatise, Vivisection or Science - A Choice to Make (1991). Morphine sends cats into a frenzy, yet it calms and anaesthetises humans. The amount of opium that can be eaten without discomfort by the hedgehog would keep the most hardened addict happy for a fortnight. Arsenic kills humans but it is harmless to guinea-pigs, chickens and monkeys. Chloroform, used successfully for decades in human surgery, is poisonous for dogs. Digitalis, which dangerously raises the blood pressure of dogs, is used to lower blood pressure for humans. The list can be lengthened at will, but these few examples should be sufficient to demonstrate that there could not be a more unreliable test for new drugs than animal experimentation. There are five basic stages in which a drug has an effect when taken internally. These are: absorption into the bloodstream, distribution to the site of action, mechanism of action, metabolism, and excretion. Considering that people of different sexes, ages, health and genetic make-up may react quite differently, it is obvious that other species often react very differently. Even a minor change, repeated at each stage, can accumulate, resulting in a major change of effect. One of the most important factors is the speed and pattern of metabolism, or the way in which a drug is broken down by the body. Scientific reports show that variation in drug metabolism between species is the rule rather than the exception. Toxic drug effects not predicted by animal testing may be seen in people if their metabolism is slower, with the potentially dangerous result from longer exposure. The anti-inflammatory drugs phenylbutazone and oxyphenbutazone, which have been responsible for an estimated 10,000 deaths world-wide, takes 72 hours for people to metabolise. however, phenylbutazone is metabolised by rhesus monkeys, dogs, rats and rabbits in eight, six, six, and three hours, respectively. Oxyphenbutazone takes only half an hour for dogs to metabolise. Another fundamental problem that makes animal testing a flawed process concerns the aetiology (cause) of the disease that the drug under test is supposed to treat. because animals don't suffer the same diseases as humans, experimenters attempt to artificially recreate spontaneous human diseases (naturally occurring diseases that arise from within) in healthy animals, and then they use these 'models' to attempt to determine the efficacy (effectiveness) of the drug in question. This is totally illogical because the artificially recreated animal disease can in no way approximate a naturally occurring human disease (nor of the same animals species for that matter). once a disease is 're-created', it is artificial and is no longer the original, natural disease. Sometimes it is possible to re-create some of the symptoms of the disease but never the disease itself. The only exception is infectious diseases, but animals do not get human infectious diseases and we do not get theirs. As well as the routine subacute and chronic toxicity tests (which involve poisoning by a substance being taken in normal quantities over a long period of time), drugs are also tested on animals for acute toxicity (poisoning due to a large amount of substance taken in a short period of time) and teratogenicity (ability to cause foetal malformations). Fraudulent Acute Toxicity Tests The LD50 is an acute toxicity test designed to indicate the human lethal dose that results from accidental or intentional overdose. The standard LD50 tests consist of forcing massive amounts of the test substance down the throats of a large number of animals to discover at what dosage-level about 50 per cent of them will die. Even if the substance is not poisonous to the animal, it will cause damaging effects by overpowering the animal's ability to cope with the sheer quantities. Most toxicologists and clinicians agree that these tests are scientifically indefensible. Professor Zbinden writes: "For the recognition of the symptomatology of acute poisoning in man, and for the determination of the human lethal dose, the LD50 in animals is of very little value." D. Lorke, from the Institute of Toxicology, Bayer AG, Germany, states that "even if the LD50 could be measured exactly and reproducibly, the knowledge of its precise numerical value would barely be of practical importance, because an extrapolation from the experimental animals to man is hardly possible." Despite the fact that the tests have no scientific validity, they are used as a crude index of acute toxicity, demanded by government regulations. according to one of Britain's largest contract laboratories, Huntingdon Research Centre, "Approximately 90 per cent of LD50 tests which are performed by this Contract Research Centre, and probably by other also, are purely to obtain a value for various legislative needs." Fraudulent Teratogenic Tests Supposedly to safeguard pregnant women form exposure of potentially teratogenic drugs, these substances are tested on various species of pregnant animals before being marketed. However, these tests are also worthless, because as Dr. Robert Sharpe explains in his book, The Cruel Deception (1988):
The ineffectiveness of the teratogenic tests is demonstrated by the fact that the malformations caused by thalidomide (a drug prescribed to pregnant women for morning sickness that caused over 10,000 grotesque birth deformities) proved very difficult to duplicate on animals, despite being tested on a large range of species. Writing in his book, Drugs as Teratogens, J. L. Schardein comments:
Further, medical historian, Hans Ruesch point out in his book, Slaughter of the Innocent (1991):
Birth Deformities on the Increase As a result of the thalidomide tragedy, there has been a massive increase in the use of test animals but this has failed to prevent further deformities. on the contrary, the malformations have increased, and more than twenty years later, on 19 July 1983, a headline in The New York Times revealed: "Physical and Mental Disabilities in Newborns Doubled in 25 Years." Furthermore, it has recently been uncovered that every year more than a quarter of a million babies (1 in 12) are born with birth defects in the United States. Criticisms From Within Because animal testing gives false and misleading data on the 'safety' and 'efficacy' of dangerous drug substances, many toxicologists and clinicians have expressed much criticism. To quote some of them:
Animal Testing Gives Hints, Indications? In support of animal testing, vivisectionists say: "We don't expect final answers from animal experiments, but just hints, indications, which encourage us to continue in a particular direction." This is, of course, sheer nonsense. Professor Pietro Croce explains:
How Should Drugs Be Tested? Vivisectionists would have the public believe that animal testing is an essential part of drug testing and evaluation, and that these tests cannot be dispensed with. This is also nonsense, as true scientific methods that are accurate and reliable are available and in current use. Drug testing and evaluation should include: the use of human tissues, cells and organs (in vitro cultures): chromatography and mass spectrometry (which separate drug substances at their molecular level to identify their properties: quantum pharmacology (using quantum mechanics to understand the molecular structure of chemicals); properly carried-out human clinical trials; and thorough reporting of drug side-effects by post-market surveillance. The Ames test used in conjunction with in vitro tests is very effective in determining teratogenic and carcinogenic (cancer-causing) properties of substances. Why Do Drug Companies Use Animal Tests? Although the previously mentioned methods have a demonstrated proven worth, drug companies still insist on using misleading animal tests, because they argue that government regulations demand them. But why would they? Bearing in mind the drug companies' criminal reputation in fraudulent drug testing and other illegal activities, with the collaboration of corrupt government and medical officials (as demonstrated by Ruesch and Braithwaite, among others), the following analysis by Hans Ruesch comes as no surprise:
To back his conclusions, Hans Ruesch has assembled massive damning evidence against the perpetrators of the phoney drug-testing fraud. this has been well-documented in his book Slaughter of the Innocent, and its sequel, Naked Empress or the Great Medical Fraud (1992). The documentary film, Hidden Crimes (1986), which is based on Hans Ruesch's books and is produced by Javier Burgos, gives a visual account of the vivisection fraud. Ruesch cited a criminal trial involving Chemie Grunenthal, the German manufacturer of thalidomide. They were incriminated for having marketed a harmful drug. Writes Ruesch:
Another example to illustrate the above point: Ruesch cites the case of Opren (the arthritis drug responsible for a number of deaths), as reported in the 12 February 19983 issue of Britain's Economist:
Doctors Agree: Vivisection is Scientific Fraud The following statements from doctors, not bound to commercial interests, contribute to the real motives behind the vivisectionists' methods of drug testing:
Conclusion on Drug Testing The inescapable conclusion is that drug companies choose animal tests over scientific methods because of the utter unreliability of animal tests. Because each animal species is unique in its physiological, biochemical, histological, morphological and other characteristics, and consequently reacts differently to substances, drug companies can produce results favourable to their interests by simply choosing the appropriate species. If their product is harmless, fine, money rolls in. If it's harmful, no problem, accusations are disposed of on the grounds that it was tested and found to be 'safe' on animals. If drugs were tested properly using true scientific methods, the vast majority of them would not be allowed onto the market because their harmfulness and ineffectiveness would be all too apparent. The constant stream of new drugs would slow to a trickle and within a few years most drug companies would go bankrupt. Drugs Are Poisons The problem is that virtually all drugs are toxic to some degree, and as Eli Lilly once said, "a drug without side-effects is no drug at all." No drug can be pinpointed to affect only the organ it is designed to treat, and most drugs have broad effects and some affect virtually every organ system in the body. Drugs are toxic because that are generally composed of artificial chemical compounds that have been synthesised in the laboratory. in the past, before drugs became big business, nearly all medicines were composed of natural plant-derived ingredients that were far safer than today's drugs. Unfortunately, the drug companies today choose to chemically synthesise the ingredients instead, because they are cheaper to produce and can be patented, giving the companies monopoly rights on their sales. For some insight into the toxic nature of the next drug your doctor tries to prescribe for you, the authors recommend that you ask him or her to look up the drug for you in their copy of MIMS (bi-monthly). These books, which doctors have at their disposal, give disturbing details on the toxic effects of individual drugs. You will discover that your doctor would more than likely be reluctant, because he or she knows after seeing the details for yourself you would most probably refuse the drug. However, be warned: the information in MIMS is only what the drug companies supply and is not a true account of how dangerous these chemical substances really are. How Many Drugs Do We Need? Already over 30 years ago, Dr. Walter Modell of Cornell University's Medical College, whom Time has described as "one of America's foremost drug experts", wrote in Clinical Pharmacology and Therapeutics:
Since 1961, the number of drug preparations marketed world-wide has increased to 205,000 with a proportional rise in new maladies. Further, Ruesch reveals:
The preceding list, taken from Vivisection: Science or Sham (by Dr. Roy Kupsinel, 1990) and Naked Empress), is just a very small sample of a far greater number of therapeutic disasters that have taken place.
Vivisection - The Distorted Issue The issue of animal experimentation has been a very contentious one for well over a century - since the time the French physiologist Claude Bernard (1813 - 1878) founded the modern vivisectionist method. Defenders of animal experimentation, through their aggressive campaigns with the help of the industry-beholden media, have largely succeeded in convincing the public that vivisection is responsible for any medical progress and that the only possible objection is solely based on animal welfare. On the contrary, medical historians such as Hans Ruesch, Dr. Beddow Bayly, Dr. Robert Sharpe and Dr. Brandon Reines, to name a few, have repeatedly demonstrated that important discoveries were made through human clinical research, observations of patients and human autopsies among other human based research methodologies, and that vivisectionists have distorted medical history in their favour. Animal experimentation has served primarily to 'prove' in animals what has already been demonstrated in people. Also, contrary to what the proponents of vivisection would have the public believe, the strongest objection to vivisection has been from the medical and scientific community. The book, 1000 Doctors (and many more) Against Vivisection (1989), by Hans Ruesch, highlights this fact. 1000 Doctors is a compilation of an impressive collection of anti-vivisection statements made by doctors and scientists from around the world. The professional verdicts that start as far back as 1824,are a reminder of the fact that there have always been members of the scientific and medical profession strongly opposed to vivisection on scientific and medical grounds. With today's medical research being heavily based on fraudulent animal experimentation, is it any wonder that diseases remain uncured and are on the increase: diseases such as cancer, diabetes, heart disease, birth defects, arthritis, muscular dystrophy, leukaemia, all kinds of mental disease, Alzheimer's, and the latest tragedy, AIDS. |